Trenbolone acetate

The drug trenbolone acetate is, without a doubt, the most powerful injectable anabolicsteroid used by Steriod.com members to gain muscle. However the fullproperties of the drug are not always fully understood. This profilewill separate fact from fiction and help steroid.com members decide iftrenbolone is right for them.

Trenbolone is similar to the highly popular steroid nandrolone, in that they are both 19-nor steroids, meaning that a testosteronemolecule has been altered at the 19th position to give us a newcompound. Unlike nandrolone however trenbolone is an excellent mass andhardening drug with the majority of gains being muscle fiber, withminimal water retention (1) It has an unbelievable anabolic (musclebuilding) score of 500. When you compare that to testosterone, whichitself is a powerful mass builder, and has an anabolic score of 100 youcan begin to fathom the muscle building potential of trenbolone. Whatmakes trenbolone so anabolic? Numerous factors come into play.Trenbolone greatly increases the level of the extremely anabolichormone IGF-1 within muscle tissue (2). And, it´s worth noting that notonly does it increase the levels of IGF-1 in muscle over two fold, italso causes muscle satellite cells (cells that repair damaged muscle)to be more sensitive to IGF-1 and other growth factors(3). The amountof DNA per muscle cell may also be significantly increased (3).

Trenbolonealso has a very strong binding affinity to the androgen receptor (A.R),binding much more strongly than testosterone (4). This is important,because the stronger a steroid binds to the androgen receptor thebetter that steroid works at activating A.R dependant mechanisms ofmuscle growth. There is also strong supporting evidence that compoundswhich bind very tightly to the androgen receptor also aid in fat loss.Think as the receptors as locks and androgens as different keys, withsome keys (androgens) opening (binding) the locks (receptors) muchbetter than others. This is not to say that AR-binding is the finalword on a steroid´s effectiveness. Anadrol doesn´t have any measurablebinding to the AR& and we all know how potent Anadrol is formass-building.

Trenbolone increases nitrogenretention in muscle tissue (5). This is of note because nitrogenretention is a strong indicator of how anabolic a substance is.However, trenbolone´s incredible mass building effects do not endthere. Trenbolone has the ability to bind with the receptors of theanti-anabolic (muscle destroying) glucocorticoid hormones (6). This mayalso has the effect of inhibiting the catabolic (muscle destroying)hormone cortisol (7).

Yet another amazing traitof trenbolone that must be noted is its ability to improve feedefficiency and mineral absorption in animals given the drug (8). Tohelp you understand what this means for you, feed efficiency is ameasurement of how much of an animals diet is converted into meat, andthe more food it takes to produce this meat, the lower the efficiency.Conversely, the less food it takes to produce meat the, higher theefficiency& well you get the idea. Animals given trenbolone gainedhigh quality weight without having their diet adjusted, thus improvingfeed efficiency. Finding new compounds which can improve feedefficiency is a billion dollar industry, and has spawned manynutritional advances in the bodybuilding world over the last fewdecades (CLA, Whey Protein, and HMB are compounds which spring to mindas having first been introduced by the livestock industry). What doesthis translate to for the hard training athlete? The food you eat willbe better utilized for building lean muscle, and vitamins and mineralsare also better absorbed which may keep you healthier during cycle.

Trenboloneis also a highly androgenic hormone, when compared with testosterone,which has an androgenic ratio of 100; trenbolone´s androgenic ratio isan astonishing 500. Highly androgenic steroids are appreciated for theeffects they have on strength as well as changing the estrogen/androgenratio, thus reducing water and under the skin. As if the report ontrenbolone was not good enough, it gets better; Trenbolone isextraordinarily good as a fat loss agent. One reason for this is itspowerful effect on nutrient partitioning (9). It is a little known factis that androgen receptors are found in fat cells as well as musclecells(10), androgens act directly on the A.R in fat cells to affect fatburning.(11) the stronger the androgen binds to the A.R, the higher thelipolytic (fat burning) effect on adipose tissue (fat)(11). Since somesteroids even increase the numbers of A.R in muscle and fat (11, 12)this fat loss effect would be amplified with the concurrent use ofother compounds, such as testosterone.

Trenbolonepromotes red blood cell production and increases the rate of glycogenreplenishment, significantly improving recovery (13). Like almost allsteroids, trenbolones effects are dose dependant with higher dosageshaving the greatest effects on body composition and strength. Mentalchanges are a notorious side effect of trenbolone use(15), androgensincrease chemicals in the brain that promote aggressive behavior(16),which can be beneficial for some athletes wanting to improve speed andpower.

Trenbolones chemical structure makes itresistant to the aromatize enzyme (conversion to estrogen) thusabsolutely no percentage of trenbolone will convert to estrogen.Trenbolone administration would not promote estrogenic side effectssuch as breast tissue growth in men (gynecomastia, bitch tits)accelerated fat gain, decline in fat break down and water retentiontrenbolone. Trenbolone is also resistant to the 5- alpha-reductaseenzyme, this enzyme reduces some steroid hormones into a moreandrogenic form, in trenbolones case however this does not matter,trenbolone boasts an androgenic ratio of 500, it can easily causeadverse androgenic side effects in any steroid.com members who areprone cases of hair loss, prostate enlargement, oily skin and acne havebeen reported. Unfortunately trenbolones potential negative sideeffects do not end there. Trenbolone is also a noted progestin: itbinds to the receptor of the female sex hormone progesterone (withabout 60% of the actual strength progesterone) (17). In sensitivesteroid.com members this can lead to bloat and breast growth worsestill, trenbolones active metabolite17beta-trenbolone has a bindingaffinity to the progesterone receptor (PgR) that is actually greaterthan progesterone itself (18). No need to panic though, theanti-estrogens letrzole or fulvestrant can lower progesterone levels,and combat any progestenic sides. The use of a 19-nor compound liketrenbolone also increases prolactin& . bromocriptine or cabergolineare often recommended to lower prolatin levels (20). Testicular atrophy(shrunken balls) may also occur; HCG used intermittently throughout acycle can prevent this. (21) It is also wise for Tren users to closelymonitor their cholesterol levels, as well as kidney function and liverenzymes, as Tren has the potential to negatively affect all of thosefunctions. Trenbolone, being a powerful progestin, will also shut downnatural testosterone production which even a relatively small dose andkeep the testosterone level suppressed for an extended period of time,this can lower libido and cause erectile dysfunction (fina dick). It isessential that you always stack trenbolone with testosterone.

Theacetate ester is a very short-chain ester attached to the trenbolonemolecule. It has an active life of 2-3 days but to keep blood levels oftrenbolone elevated and steady, daily injections are often recommended.The acetate ester provides a rapid and high concentration of thehormone which is beneficial to those seeking quick gains, coupled witha rapid clearing time the acetate ester can be discontinued on theonset of adverse side effects.

Now that theproperties of trenbolone acetate have been explained we can betterunderstand how to use it in order to maximize its advantages. Evidencesuggests that trenbolone when stacked with estrogen promotes moreweight gain that trenbolone alone(22), now I´m not telling you to gopop some birth control with your trenbolone but the addition ofaromatizing orals such as dianabol and a long estered testosterone suchas cypionate or enanthate would produce great gains in a bulking cycle.For a cutting cycle trenbolone is the best choice you have; trenbolonespowerful effect on nutrient shuttling allows a user to restrictcalories and remain in a state of positive nitrogen balance (rememberwhat that means?). The cortisol reducing effect and binding to theglucocorticoid receptor will greatly reduce the catabolic effects ofharsh dieting and excessive amounts of cardio& not to mention thattrenbolone itself may burn fat (due to it´s strong AR-binding). A goodchoice to stack with tren in a cutting cycle is Winstrol. Winstrol hasa low binding affinity to the AR and thus will act in your body invastly different ways than the Tren (i.e. in non-receptor mediatedaction). In addition, Winstrol is a DHT-based drug and Tren is a19-nor& throw in some Testosterone (prop), and you´ll have acutting cycle which takes advantage of all 3 major families of Anabolic Steroids (Testosterone, 19-nor, and DHT), as well as vastly different AR-binding affinities and mechanisms of action.

Ironically,even though Tren is an excellent contest prep drug, it lowers yourthyroid level(23), and this raises prolactin. I recommend taking T3(25mcgs/day) along with your Tren to avoid elevating your prolactin toohigh via this route.

Also, this drug is a poorchoice for athletes who rely on cardiovascular fitness to play a sport.Tren, anecdotally at least, reduces many athletes ability to sustainhigh levels of endurance. Unfortunately, this makes Tren a poor choicefor many.

As of now the main source of trenboloneis from implants for cattle being converted into an injectable ortransdermal compound, from powder, and of course Underground Labs."Home brewing" powder or cattle implants seems to be the preferredmethod of obtaining injectable trenbolone acetate, because the userwould have much more control over the potency and sterility of thedrug. Trenbolone is much more expensive than other anabolic steroidsranging from 15 U.S dollars per gram of powder or 150 U.S for a single10 ml bottle. The cost of trenbolone should not matter, it is worthevery penny.