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Roaccutan® (Isotretinoin)
Accutan is used in the treatment of acne. Four to five months ofisotretinoin treatment usually leads to clearing of acne for one yearor more after the medicine is stopped.
Most other acne-controlling medicines are antibacterial agents, which are effective only if the medicine is used daily.
Isotretinoin has significant side effects: (percentages are the ratioof people who received the side-effect). Chapped lips 90% , dry skinand itching 80% - the use of daily alpha hydroxacids will help preventthis side effect. Dryness of nose, mild nosebleed 80%, Irritation ofthe eyelids and eyes 40% - Vitamin E 400 IU each day may lessen thisside effect. Joint and muscle pains 15%, Temporary hair thinning 10%,Rash 7%, Intestinal symptoms 5%, Urinary symptoms 5%, Headache 5%,Increased sensitivity to sunburn 5%, Decreased night vision <1%,Depression, thoughts of suicide <1%.
Isotretinoin may increase the level of blood fats, sometimes to riskylevels. Occasionally it may affect the liver. That is why regular bloodtests are necessary when you are taking isotretinoin. These tests mustbe done when you have fasted for 12 hours (no breakfast), so that theblood fat determinations are reliable. A baseline blood chemistry testis established before patients start isotretinoin.
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